In 2000, her book Born in Bondage won the Julia Cherry Spruill Publication Prize for Best Book in Southern Women’s History, given by the Southern Association for Women Historians. Schwartz is the recipient of two fellowships from the National Endowment for the Humanities and other research awards from the American Historical Association, the John Nicholas Brown Center for the Study of American Civilization at Brown University, the American College of Obstetricians and Gynecologists/McNeil Foundation and from the University of Rhode Island, including its Center for the Humanities. She has begun another book on the First Ladies ( Scandal in the White House: First Ladies and Presidential Deceits), which argues that the reaction of First Ladies to the scandalous behavior of husbands has mattered for the stability of the nation. Her latest book, called Ties That Bound: Founding First Ladies and Slaves (Chicago University Press in 2016), depicts the world created by Martha Washington, Martha Jefferson, Martha (Patsy) Jefferson Randolph, Dolley Madison and the people they enslaved. She is currently professor emeritus of history at URI and an independent scholar and writer. taught at Anne Arundel Community College, Arnold, Maryland, before accepting a position at the University of Rhode Island where for twenty years she offered courses in the history of slavery and in the history of the early United States. Study nots arnold marie schwartz college of pharmacy and health sciences long island university typing store operations assignment learning outcome. All rights reserved.Marie Jenkins Schwartz, Ph.D. In summary, these findings strongly support the involvement of calcium in the penetration-enhancing effect of menthol.ĭiphenhydramine hydrochloride (Pubchem CID: 8980) TRPM8 channel calcium cutaneous penetration diltiazem hydrochloride (Pubchem CID: 62920) l-menthol (Pubchem CID: 16666) lidocaine hydrochloride monohydrate (Pubchem CID: 6314) menthol microdialysis transdermal verapamil hydrochloride (Pubchem CID: 62969).Ĭopyright © 2017 American Pharmacists Association®. The College of Pharmacy (The Arnold & Marie Schwartz College of Pharmacy and Health Sciences) offers the Doctor of Pharmacy (Pharm.D.) degree program to prepare students for entry-level pharmacy practice. The gels containing menthol showed higher penetration of drugs than those without whereas the addition of the CCB consistently inhibited the penetration-enhancing effects of menthol. Dermis concentration profiles were assessed with microdialysis. In vivo experiments were performed for each drug/menthol/CCB combination gel by applying 4 formulations on a shaved rabbit's dorsum on the same day. In vitro studies showed no effect of the CCB on the release of the drugs either with or without menthol. We formulated 16 gels: (i) drug-alone (diphenhydramine or lidocaine), (ii) drug with menthol, (iii) drug, menthol, and calcium channel blocker (CCB verapamil or diltiazem), and (iv) drug and CCB. Founded in 1886, it is one of the oldest pharmacy schools in the United States today. Because calcium is present in the entire epidermis, the purpose of this study is to evaluate whether the aforementioned properties of menthol are also related to its penetration-enhancing effects. The Arnold and Marie Schwartz College of Pharmacy, formerly known as the Brooklyn College of Pharmacy, is a graduate school of Long Island University (LIU)'s Brooklyn Campus. A decrease in extracellular Ca 2+ due to the activation of the transient receptor potential melastatin 8 receptor produces inhibition of E-cadherin expression that is responsible for cell-cell adhesion. Literature shows a growing interest in menthol's interactions with the transient receptor potential melastatin 8. Menthol is a naturally occurring terpene used as a penetration enhancer in topical and transdermal formulations.
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